![]() Fluid therapy can also have an impact on drug therapy. Maintenance electrolyte requirements must be taken into account, with particular attention paid to sodium requirements, as recent evidence suggests that sodium needs in hospitalized children are higher than originally thought. Accounting for deficits when determining the fluid infusion rate is an important factor in treating dehydrated patients deficit fluid is generally administered over the first 24 hours of hospitalization. The Holliday-Segar equation remains the standard method for calculating maintenance fluid requirements. Fluid therapy is divided into maintenance, deficit, and replacement requirements. ![]() Managing fluids and electrolytes in children is an important skill for pharmacists, who can play an important role in monitoring therapy.
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